{"id":1697,"date":"2026-10-06T12:40:51","date_gmt":"2026-10-06T12:40:51","guid":{"rendered":"https:\/\/dev.ich.org\/index.php\/guidelines\/s3b\/"},"modified":"2026-10-06T12:40:51","modified_gmt":"2026-10-06T12:40:51","slug":"s3b","status":"publish","type":"guideline","link":"https:\/\/dev.ich.org\/index.php\/guidelines\/s3b\/","title":{"rendered":"S3B \u2013 Pharmacokinetics: Guidance for Repeated Dose Tissue Distribution Studies"},"content":{"rendered":"<p>The ICH Harmonised Guideline was finalised under <em>Step 4 <\/em>in October 1994. This document gives guidance on circumstances when repeated dose tissue distribution studies should be considered (e.g., when appropriate data cannot be derived from other sources). It also gives recommendations on the conduct of such studies.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The ICH Harmonised Guideline was finalised under Step 4 in October 1994. This document gives guidance on circumstances when repeated dose tissue distribution studies should be considered (e.g., when appropriate data\u2026<\/p>\n","protected":false},"featured_media":0,"template":"","guideline_category":[19],"guideline_tag":[],"rd_phase":[],"class_list":["post-1697","guideline","type-guideline","status-publish","hentry","guideline_category-safety"],"acf":[],"_links":{"self":[{"href":"https:\/\/dev.ich.org\/index.php\/wp-json\/wp\/v2\/guideline\/1697","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dev.ich.org\/index.php\/wp-json\/wp\/v2\/guideline"}],"about":[{"href":"https:\/\/dev.ich.org\/index.php\/wp-json\/wp\/v2\/types\/guideline"}],"version-history":[{"count":0,"href":"https:\/\/dev.ich.org\/index.php\/wp-json\/wp\/v2\/guideline\/1697\/revisions"}],"wp:attachment":[{"href":"https:\/\/dev.ich.org\/index.php\/wp-json\/wp\/v2\/media?parent=1697"}],"wp:term":[{"taxonomy":"guideline_category","embeddable":true,"href":"https:\/\/dev.ich.org\/index.php\/wp-json\/wp\/v2\/guideline_category?post=1697"},{"taxonomy":"guideline_tag","embeddable":true,"href":"https:\/\/dev.ich.org\/index.php\/wp-json\/wp\/v2\/guideline_tag?post=1697"},{"taxonomy":"rd_phase","embeddable":true,"href":"https:\/\/dev.ich.org\/index.php\/wp-json\/wp\/v2\/rd_phase?post=1697"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}