{"id":1775,"date":"2026-10-06T13:11:38","date_gmt":"2026-10-06T13:11:38","guid":{"rendered":"https:\/\/dev.ich.org\/index.php\/guidelines-under-development\/m7-addendum\/"},"modified":"2026-10-06T13:11:38","modified_gmt":"2026-10-06T13:11:38","slug":"m7-addendum","status":"publish","type":"draft_guideline","link":"https:\/\/dev.ich.org\/index.php\/guidelines-under-development\/m7-addendum\/","title":{"rendered":"M7 Addendum \u2013 Risk Assessment and Control of Nitrosamine Impurities"},"content":{"rendered":"<p>This topic was endorsed by the ICH Assembly in June 2024 and the M7 Sub-group has been established to develop an addendum to the M7 Guideline on Assessment and Control of DNA Reactive (mutagenic) Impurities to address safety assessment and establishment of appropriate controls for nitrosamine impurities.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>This topic was endorsed by the ICH Assembly in June 2024 and the M7 Sub-group has been established to develop an addendum to the M7 Guideline on Assessment and Control of DNA Reactive (mutagenic) Impurities to address\u2026<\/p>\n","protected":false},"featured_media":0,"template":"","guideline_category":[20],"guideline_tag":[],"rd_phase":[],"class_list":["post-1775","draft_guideline","type-draft_guideline","status-publish","hentry","guideline_category-multidisciplinary"],"acf":[],"_links":{"self":[{"href":"https:\/\/dev.ich.org\/index.php\/wp-json\/wp\/v2\/draft_guideline\/1775","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dev.ich.org\/index.php\/wp-json\/wp\/v2\/draft_guideline"}],"about":[{"href":"https:\/\/dev.ich.org\/index.php\/wp-json\/wp\/v2\/types\/draft_guideline"}],"version-history":[{"count":0,"href":"https:\/\/dev.ich.org\/index.php\/wp-json\/wp\/v2\/draft_guideline\/1775\/revisions"}],"wp:attachment":[{"href":"https:\/\/dev.ich.org\/index.php\/wp-json\/wp\/v2\/media?parent=1775"}],"wp:term":[{"taxonomy":"guideline_category","embeddable":true,"href":"https:\/\/dev.ich.org\/index.php\/wp-json\/wp\/v2\/guideline_category?post=1775"},{"taxonomy":"guideline_tag","embeddable":true,"href":"https:\/\/dev.ich.org\/index.php\/wp-json\/wp\/v2\/guideline_tag?post=1775"},{"taxonomy":"rd_phase","embeddable":true,"href":"https:\/\/dev.ich.org\/index.php\/wp-json\/wp\/v2\/rd_phase?post=1775"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}