{"id":1768,"date":"2026-10-06T13:11:36","date_gmt":"2026-10-06T13:11:36","guid":{"rendered":"https:\/\/dev.ich.org\/index.php\/guidelines-under-development\/e20\/"},"modified":"2026-10-06T13:11:36","modified_gmt":"2026-10-06T13:11:36","slug":"e20","status":"publish","type":"draft_guideline","link":"https:\/\/dev.ich.org\/index.php\/guidelines-under-development\/e20\/","title":{"rendered":"E20 \u2013 Adaptive Designs for Clinical Trials"},"content":{"rendered":"<p>This topic was endorsed by the ICH Assembly in June 2018.<\/p>\n<p>The E20 EWG is working on the development of a new E20 Guideline on \u201cAdaptive Clinical Trials\u201d on the design, conduct, analysis, and interpretation of adaptive clinical trials that provides a transparent and harmonized set of principles for the regulatory review of these studies in a global drug development program. These principles should also provide the flexibility to evaluate \/ discuss innovative approaches to clinical trial design throughout the development process.<\/p>\n<p>Following MC approval in June 2025 the E20 Guideline title was changed to &#8220;<em>Adaptive Designs for Clinical Trials<\/em>&#8220;.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>This topic was endorsed by the ICH Assembly in June 2018. The E20 EWG is working on the development of a new E20 Guideline on \u201cAdaptive Clinical Trials\u201d on the design, conduct, analysis, and interpretation of adaptive\u2026<\/p>\n","protected":false},"featured_media":0,"template":"","guideline_category":[9],"guideline_tag":[],"rd_phase":[],"class_list":["post-1768","draft_guideline","type-draft_guideline","status-publish","hentry","guideline_category-efficacy"],"acf":[],"_links":{"self":[{"href":"https:\/\/dev.ich.org\/index.php\/wp-json\/wp\/v2\/draft_guideline\/1768","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dev.ich.org\/index.php\/wp-json\/wp\/v2\/draft_guideline"}],"about":[{"href":"https:\/\/dev.ich.org\/index.php\/wp-json\/wp\/v2\/types\/draft_guideline"}],"version-history":[{"count":0,"href":"https:\/\/dev.ich.org\/index.php\/wp-json\/wp\/v2\/draft_guideline\/1768\/revisions"}],"wp:attachment":[{"href":"https:\/\/dev.ich.org\/index.php\/wp-json\/wp\/v2\/media?parent=1768"}],"wp:term":[{"taxonomy":"guideline_category","embeddable":true,"href":"https:\/\/dev.ich.org\/index.php\/wp-json\/wp\/v2\/guideline_category?post=1768"},{"taxonomy":"guideline_tag","embeddable":true,"href":"https:\/\/dev.ich.org\/index.php\/wp-json\/wp\/v2\/guideline_tag?post=1768"},{"taxonomy":"rd_phase","embeddable":true,"href":"https:\/\/dev.ich.org\/index.php\/wp-json\/wp\/v2\/rd_phase?post=1768"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}